Hormone replacement therapy and cardiovascular disease revisited
نویسندگان
چکیده
منابع مشابه
Hormone replacement therapy and cardiovascular disease.
Oestrogen alone probably confers a degree of protection against ischaemic heart disease and stroke and is appropriate for women requiring hormone replacement therapy (HRT) who have undergone hysterectomy. However, the cardiovascular effects of the progestogens used with oestrogen in the much larger number of women who have not undergone hysterectomy are unknown. Some widely used progestogens ha...
متن کاملPostmenopausal hormone replacement therapy and cardiovascular disease.
Cardiovascular disease is the leading cause of mortality in postmenopausal women in developed countries. A possible cardioprotective role of hormone replacement therapy (HRT) is suggested by epidemiologic studies of HRT and reduced risk of coronary heart disease, as well as by randomized trials of HRT and lipid subfractions. Estrogen has beneficial effects on the lipid profile, raising high-den...
متن کامل[Cardiovascular disease and hormone replacement therapy].
In Canada, cardiovascular disease (CVD) is the leading cause of mortality. In 1990, CVD killed 36,266 Canadian women. This represents 41 percent of deaths in women and is greater than all deaths due to cancer.' On average, Canadian women outlive men by seven years. During this period, CVD is second only to joint and bone dise'ase in limiting activities and reducing the autonomy of these women.2...
متن کاملPostmenopausal Hormone Replacement Therapy and Cardiovascular Disease
Heart disease is the leading cause of death among postmenopausal American women. Although early observational studies suggested that hormone replacement therapy (HRT) might decrease these risks, prospective, experimental studies have not supported these results. With the recent release of these data in the media, clinicians are receiving numerous questions concerning HRT. This article reviews t...
متن کاملHormone replacement therapy and inflammation: interactions in cardiovascular disease.
Inflammation plays a central role in the pathogenesis of many forms of vascular disease, including atherosclerosis. Atherogenesis begins with endothelial damage, and the damaged endothelium expresses adhesion molecules, chemokines, and proinflammatory cytokines that direct atherosclerotic plaque formation and spill into the circulation as biomarkers of atherosclerotic disease risk. Menopausal h...
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ژورنال
عنوان ژورنال: Menopause International
سال: 2009
ISSN: 1754-0453
DOI: 10.1258/mi.2009.009018